Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | CES1 | P23141 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257380 | 0.93 | CES2 (0.50) | CES2CES1TDP1MEN1KMT2A | |
| SCHEMBL6753538 | 0.86 | CES2 (0.47) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL7606998 | 0.78 | EPHX2 (0.50) | CES2CES1EPHX2MEN1KMT2A | |
| SCHEMBL28545475 | 0.78 | EPHX2 (0.50) | CES2CES1EPHX2MEN1KMT2A | |
| SCHEMBL2640406 | 0.77 | CES2 (0.45) | CES2CES1EPHX2MEN1KMT2A | |
| SCHEMBL29060487 | 0.76 | CES2 (0.54) | CES2CES1EPHX2TDP1MEN1 | |
| SCHEMBL14722425 | 0.76 | CES2 (0.54) | CES2CES1EPHX2TDP1MEN1 | |
| SCHEMBL27871360 | 0.75 | CES2 (0.50) | CES2CES1EPHX2MEN1KMT2A | |
| SCHEMBL5982815 | 0.75 | CES2 (0.50) | CES2CES1EPHX2MEN1KMT2A | |
| SCHEMBL11263922 | 0.75 | SMN1; SMN2 (0.43) | CES2CES1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |