Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606998 | 1.00 | EPHX2 (0.50) | EPHX2MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL45252 | 0.80 | RAB9A (0.47) | KMT2AALDH1A1PAM | |
| SCHEMBL7829859 | 0.78 | CES2 (0.53) | EPHX2MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL2589963 | 0.78 | MEN1 (0.58) | EPHX2MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL21629342 | 0.77 | DNM1 (0.47) | EPHX2MEN1KMT2AALDH1A1CETP | |
| SCHEMBL7564307 | 0.76 | ALDH1A1 (0.57) | EPHX2MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL9802928 | 0.76 | ALDH1A1 (0.57) | EPHX2MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL1322235 | 0.76 | ALDH1A1 (0.57) | EPHX2MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL3836540 | 0.76 | ALDH1A1 (0.57) | EPHX2MEN1KMT2AALDH1A1CES2 | |
| SCHEMBL296362 | 0.76 | ALDH1A1 (0.57) | EPHX2MEN1KMT2AALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710072-A | Therapeutic methods and compositions for treating biliary tract cancers using Devista | 基石制药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116669731-A | Therapeutic methods and compositions for treating pancreatic cancer using Devista | 基石制药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-112469405-A | Therapeutic methods and compositions for treating pancreatic cancer using 6, 8-bis (benzylthio) octanoic acid | 拉斐尔制药股份有限公司 | 2021-03-09 | — | — | CN | disclosed |