Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 11/20 | 0.60 |
| ▸ | AR | P10275 | 7/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614871 | 1.00 | PGR (0.60) | PGRARNR3C2CYP3A4NR3C1 | |
| SCHEMBL8011421 | 0.83 | PGR (0.62) | PGRARNR3C2CYP3A4NR3C1 | |
| SCHEMBL13768846 | 0.83 | PGR (0.62) | PGRARNR3C2CYP3A4NR3C1 | |
| SCHEMBL9019789 | 0.82 | PGR (0.69) | PGRARCYP3A4NR3C1 | |
| SCHEMBL8425124 | 0.79 | PGR (0.62) | PGRARNR3C2CYP3A4NR3C1 | |
| SCHEMBL8719020 | 0.78 | PGR (0.59) | PGRARNR3C2CYP3A4NR3C1 | |
| SCHEMBL12949428 | 0.78 | AR (0.66) | PGRARNR3C2CYP3A4NR3C1 | |
| SCHEMBL11424896 | 0.77 | PGR (0.70) | PGRARCYP3A4NR3C1CHRM2 | |
| SCHEMBL8423621 | 0.77 | PGR (0.63) | PGRARNR3C2CYP3A4NR3C1 | |
| SCHEMBL13768465 | 0.76 | PGR (0.62) | PGRARNR3C2CYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491803-B1 | IMPLANTABLE DELIVERY DISPENSER | ALZA CORP (US) | 1994-07-20 | — | — | EP | claimed |
| US-8491472-B2 | Methods and systems for submucosal implantation of a device for diagnosis and treatment with a therapeutic agent | APOLLO ENDOSURGERY, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| US-20120071812-A1 | Methods and Systems for Submucosal Implantation of a Device for Diagnosis and Treatment with a Therapeutic Agent | APOLLO ENDOSURGERY, INC. | 2012-03-22 | — | — | US | disclosed |
| US-8066689-B2 | Methods and systems for submucosal implantation of a device for diagnosis and treatment with a therapeutic agent | APOLLO ENDOSURGERY, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20090018604-A1 | Methods And Systems for Submucosal Implantation of a Device For Diagnosis and Treatment with a Therapeutic Agent | APOLLO ENDOSURGERY, INC. | 2009-01-15 | — | — | US | disclosed |
| US-5660847-A | Implantable delivery dispenser comprising exit port | ALZA CORPORATION (US) | 1997-08-26 | — | — | US | disclosed |
| EP-0491803-B1 | IMPLANTABLE DELIVERY DISPENSER | ALZA CORP (US) | 1994-07-20 | — | — | EP | disclosed |
| US-5112614-A | IMPLANTABLE DELIVERY DISPENSER | ALZA CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |