Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.59 |
| ▸ | AR | P10275 | 6/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425124 | 0.82 | PGR (0.62) | PGRARNR3C2NR3C1LMNA | |
| SCHEMBL8718930 | 0.81 | PGR (0.50) | PGRARNR3C2NR3C1LMNA | |
| SCHEMBL8423621 | 0.80 | PGR (0.63) | PGRARNR3C2NR3C1LMNA | |
| SCHEMBL9614871 | 0.78 | PGR (0.60) | PGRARNR3C2NR3C1LMNA | |
| SCHEMBL782987 | 0.78 | PGR (0.60) | PGRARNR3C2NR3C1LMNA | |
| SCHEMBL11424896 | 0.76 | PGR (0.70) | PGRARNR3C1LMNACYP3A4 | |
| Norgestomet SCHEMBL140381 | 0.74 | PGR (1.00) | PGRARNR3C2NR3C1LMNA | |
| Norgestomet SCHEMBL11794624 | 0.74 | PGR (1.00) | PGRARNR3C2NR3C1LMNA | |
| Norgestomet SCHEMBL140382 | 0.74 | PGR (1.00) | PGRARNR3C2NR3C1LMNA | |
| SCHEMBL24102654 | 0.74 | PGR (0.56) | PGRARNR3C2NR3C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712264-A | 17-spiromethylene steroids | AKZO NOBEL N.V. (NL) | 1998-01-27 | — | — | US | disclosed |