SCHEMBL7829893

SCHEMBL7829893

COc1ccc2c(c1)C(=N)NC2(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
MEN1 O00255 5/20 0.39
MAPT P10636 5/20 0.39
KMT2A Q03164 5/20 0.39
KDM4E B2RXH2 2/20 0.39
TSHR P16473 1/20 0.39
GFER P55789 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PDK2 Q15119 1/20 0.39
AKR1B1 P15121 3/20 0.38
AKR1A1 P14550 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
PDE7A Q13946 2/20 0.36
SNCA P37840 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7817179 0.86 MEN1 (0.40) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL7828755 0.86 ALDH1A1 (0.36) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL7827487 0.84 ALDH1A1 (0.43) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL7830483 0.83 MAOB (0.49) MEN1MAPTKMT2ATSHRPDK2
SCHEMBL7830753 0.82 MEN1 (0.40) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL7816279 0.82 PDK2 (0.39) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL7827289 0.79 PPOX (0.39) ALDH1A1KDM4EHSD17B10PDK2AKR1B1
SCHEMBL7830530 0.78 PDK2 (0.42) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL7827204 0.78 PDK2 (0.42) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL7824598 0.77 ALDH1A1 (0.34) ALDH1A1HSD17B10HPGDCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed