Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | UTRN | P46939 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27874334 | 0.81 | NOTUM (0.54) | NOTUMRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL3491241 | 0.81 | AURKA (0.48) | NOTUMKDM4EMAPTTHRBGAA | |
| SCHEMBL27857785 | 0.78 | RAB9A (0.59) | NOTUMRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL27418746 | 0.78 | RAB9A (0.64) | NOTUMRAB9ANPC1HTTKDM4E | |
| SCHEMBL12360483 | 0.77 | NPC1 (0.63) | NOTUMRAB9ANPC1HTTKDM4E | |
| SCHEMBL14452782 | 0.77 | KDM4E (0.66) | NOTUMRAB9ANPC1HTTKDM4E | |
| SCHEMBL408280 | 0.77 | RAB9A (0.57) | NOTUMRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL9269014 | 0.76 | MAPT (0.46) | NOTUMRAB9AMAPTSMN1; SMN2THRB | |
| SCHEMBL21776908 | 0.76 | NOTUM (1.00) | NOTUMKDM4EPTGS2MAOBCYP1A2 | |
| SCHEMBL8567669 | 0.75 | MAPT (0.48) | NOTUMRAB9ANPC1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670836-B1 | PYRIDYL-1,2,4-THIADIAZOLES AS PEST-CONTROL AGENTS | BAYER AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-6100402-A | Pyridyl-1,2,4-thiadiazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| US-6031104-A | Pyridyl-1,2,4-thiadiazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-5756523-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5633267-A | FUNGICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |
| EP-0670836-A1 | PYRIDYL-1,2,4-THIADIAZOLES AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012496-A1 | PYRIDYL-1,2,4-THIADIAZOLES AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1994-06-09 | — | — | WO | disclosed |