Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832027 | 0.86 | LMNA (0.49) | RAB9ANPC1NPSR1ALDH1A1GAA | |
| SCHEMBL7819253 | 0.86 | LMNA (0.50) | RAB9ANPC1NPSR1ALDH1A1GAA | |
| SCHEMBL7830921 | 0.85 | LMNA (0.50) | RAB9ANPC1NPSR1ALDH1A1GAA | |
| SCHEMBL7819362 | 0.82 | LMNA (0.52) | RAB9ANPC1NPSR1ALDH1A1GAA | |
| SCHEMBL7820036 | 0.82 | RAB9A (0.59) | RAB9ANPC1GAAPOLBMAPT | |
| SCHEMBL6222546 | 0.81 | RAB9A (0.60) | RAB9ANPC1GAAPOLBMAPT | |
| SCHEMBL7830618 | 0.81 | RAB9A (0.52) | RAB9ANPC1NPSR1ALDH1A1GAA | |
| SCHEMBL7826384 | 0.81 | KDM4E (0.51) | RAB9ANPC1NPSR1ALDH1A1GAA | |
| SCHEMBL7830964 | 0.81 | MAPT (0.50) | RAB9ANPC1NPSR1ALDH1A1GAA | |
| SCHEMBL7834273 | 0.80 | RAB9A (0.59) | RAB9ANPC1NPSR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764165-B1 | PREPARATION OF STEREOCHEMICALLY PURE OXIMES WITH MUSCARINIC ACTIVITY | WARNER LAMBERT CO (US) | 2001-11-07 | — | — | EP | claimed |
| US-5346911-A | Analgesics, cognition activators, treatment of alzheimer*s s disease | WARNER-LAMBERT COMPANY (US) | 1994-09-13 | — | — | US | claimed |
| EP-0764165-B1 | PREPARATION OF STEREOCHEMICALLY PURE OXIMES WITH MUSCARINIC ACTIVITY | WARNER LAMBERT CO (US) | 2001-11-07 | — | — | EP | disclosed |
| US-5514812-A | Preparation of stereochemically pure oximes with muscarinic activity | WARNER-LAMBERT COMPANY (US) | 1996-05-07 | — | — | US | disclosed |
| US-5346911-A | Analgesics, cognition activators, treatment of alzheimer*s s disease | WARNER-LAMBERT COMPANY (US) | 1994-09-13 | — | — | US | disclosed |