Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNB1 | Q14721 | 8/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 7/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216984 | 0.76 | CYP1A2 (0.47) | KCNB1KCNA5CTSAPTGDR2LRRK2 | |
| SCHEMBL13801391 | 0.76 | PDPK1 (0.55) | KCNB1KCNA5CTSAPDPK1 | |
| SCHEMBL28405984 | 0.74 | PDPK1 (0.51) | KCNB1KCNA5CTSAPDPK1 | |
| SCHEMBL5888543 | 0.74 | PDPK1 (0.51) | KCNB1KCNA5CTSAPDPK1 | |
| SCHEMBL29793545 | 0.74 | PDPK1 (0.51) | KCNB1KCNA5CTSAPDPK1 | |
| SCHEMBL28866312 | 0.72 | KCNB1 (0.46) | KCNB1KCNA5CTSAPTGDR2LRRK2 | |
| SCHEMBL31079263 | 0.72 | ALDH1A1 (0.41) | CTSA | |
| SCHEMBL20545939 | 0.72 | CTSA (0.57) | CTSAPTGDR2 | |
| SCHEMBL20545938 | 0.72 | CTSA (0.57) | CTSAPTGDR2 | |
| SCHEMBL30671345 | 0.71 | KCNB1 (0.51) | KCNB1KCNA5CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124810-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026202-A1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-05-11 | — | — | WO | disclosed |