Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CTSA | P10619 | 8/20 | 0.36 |
| ▸ | RBBP9 | O75884 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449339 | 0.81 | CTSA (0.33) | ALDH1A1CTSARAB9AHSD17B10 | |
| SCHEMBL6009307 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CTSARAB9AHSD17B10 | |
| SCHEMBL9107229 | 0.78 | ALDH1A1 (0.36) | ALDH1A1CTSARAB9AHSD17B10MAPT | |
| SCHEMBL5449342 | 0.77 | ALDH1A1 (0.33) | ALDH1A1CTSAHSD17B10 | |
| SCHEMBL5585939 | 0.77 | ALDH1A1 (0.43) | ALDH1A1CTSARAB9AHSD17B10L3MBTL1 | |
| SCHEMBL1007892 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CTSAHSD17B10HTT | |
| SCHEMBL7470027 | 0.74 | NPC1 (0.42) | ALDH1A1CTSARBBP9RAB9AHSD17B10 | |
| SCHEMBL8366794 | 0.73 | ALDH1A1 (0.39) | ALDH1A1CTSARAB9A | |
| SCHEMBL7830810 | 0.72 | KCNB1 (0.44) | CTSA | |
| SCHEMBL7686450 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CTSARAB9AHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651872-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155601-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-07-25 | — | — | WO | disclosed |