Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832560 | 0.90 | TDP1 (0.40) | ALDH1A1HTTRXFP1KDM4EMAPT | |
| SCHEMBL7830610 | 0.82 | SLC10A2 (0.47) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL7829696 | 0.81 | SLC10A2 (0.49) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL8132030 | 0.81 | SLC10A2 (0.46) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL7829897 | 0.81 | SLC10A2 (0.48) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL7830548 | 0.80 | SLC10A2 (0.46) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL8138537 | 0.80 | SLC10A2 (0.46) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL7819541 | 0.80 | SLC10A2 (0.55) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL8734614 | 0.80 | SLC10A2 (0.48) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL7829702 | 0.79 | SMN1; SMN2 (0.51) | SLC10A2ALDH1A1GAATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |
| EP-0567107-A1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-27 | — | — | EP | claimed |
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5948782-A | ANTIINFLAMMATORY AGENT; RHEUMATIC DISEASES | TAKEDA CHEMICAL (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0567107-A1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |