SCHEMBL78319

SCHEMBL78319

CCCCCCCC[Al](Oc1c(C(C)(C)C)cc(C)cc1C(C)(C)C)Oc1c(C(C)(C)C)cc(C)cc1C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CA2 P00918 1/20 0.35
POLB P06746 1/20 0.35
TYR P14679 1/20 0.35
CNR2 P34972 6/20 0.34
HSPA5 P11021 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
CNR1 P21554 4/20 0.32
NR5A2 O00482 1/20 0.31
NR5A1 Q13285 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585846 0.88 CYP3A4 (0.36) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CA2
SCHEMBL76761 0.83 CA2 (0.33) ALDH1A1CA2
SCHEMBL6054742 0.83 CA2 (0.33) ALDH1A1CA2
SCHEMBL2279867 0.81 CYP2D6 (0.38) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CA2
SCHEMBL937756 0.80 SMN1; SMN2 (0.42) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CA2
SCHEMBL8760276 0.76 CA2 (0.35) SMN1; SMN2ALDH1A1CA2NR5A2NR5A1
SCHEMBL585179 0.75 SMN1; SMN2 (0.41) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CA2
SCHEMBL585869 0.73 SMN1; SMN2 (0.42) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CA2
SCHEMBL78216 0.72 SMN1; SMN2 (0.38) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CA2
SCHEMBL6395982 0.72 CNR2 (0.36) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878789-B2 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 2005-04-12 US claimed
US-6831144-B2 Containing, in addition to an anionic polymerization initiator, a organoaluminum compound containing aryloxy groups, a Lewis base, and an ether or a tertiary amine KURARAY CO., LTD. (JP) 2004-12-14 US claimed
EP-0945470-B1 Preparation process of acrylic acid ester polymer KURARAY CO (JP) 2004-10-13 EP claimed
US-20020032290-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 2002-03-14 US claimed
US-6329480-B1 POLYMERIZING ACRYLIC ACID ESTER, ACRYLIC/METHACRYLIC MONOMER PRESENCE OF AN ORGANOLITHIUM COMPOUND AND AN ORGANOALUMINUM COMPOUND TO FORM BLOCK COPOLYMER KURARAY CO., LTD. (JP) 2001-12-11 US claimed
EP-0945470-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 1999-09-29 EP claimed
US-12281185-B2 Anionic polymerization process and polymer production method KURARAY CO., LTD. (JP) 2025-04-22 US disclosed
EP-3845570-B1 ANIONIC POLYMERIZATION PROCESS AND POLYMER PRODUCTION METHOD KURARAY CO (JP) 2024-10-09 EP disclosed
US-11845818-B2 Active energy ray crosslinkable thermoplastic polymer and composition containing the same KURARAY CO., LTD. (JP) 2023-12-19 US disclosed
CN-113453898-B Active energy ray-crosslinkable thermoplastic polymer and composition containing same 株式会社可乐丽 2023-10-20 CN disclosed
US-11613602-B2 (Meth)acrylic block copolymer and active energy ray curable composition containing the same KURARAY CO., LTD. (JP) 2023-03-28 US disclosed
CN-111356712-B (meth) acrylic block copolymer and active energy ray-curable composition containing same 株式会社可乐丽 2023-01-31 CN disclosed
CN-112601765-B Anionic polymerization method and method for producing polymer 株式会社可乐丽 2022-10-25 CN disclosed
US-6555637-B1 In anionic polymerization using an anionic polymerization initiator, a tertiary organoaluminum compound (A) having AL-O-Ar (Ar= aromatic ring) formula, and a Lewis base (B) selected from the group containing tertiary polyamine KURARAY CO., LTD. (JP) 2003-04-29 US disclosed
US-20020183472-A1 Biocompatible material TERUMO KABUSHIKI KAISHA (JP) 2002-12-05 US disclosed
EP-1254922-A2 Polyalkoxyalkyl (meth)acrylates and preparation thereof TERUMO KABUSHIKI KAISHA (JP) 2002-11-06 EP disclosed
US-20020032290-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 2002-03-14 US disclosed
US-6329480-B1 POLYMERIZING ACRYLIC ACID ESTER, ACRYLIC/METHACRYLIC MONOMER PRESENCE OF AN ORGANOLITHIUM COMPOUND AND AN ORGANOALUMINUM COMPOUND TO FORM BLOCK COPOLYMER KURARAY CO., LTD. (JP) 2001-12-11 US disclosed
EP-1078942-A1 Anionic polymerization process, and process for producing a polymer by the anionic polymerization process KURARAY CO., LTD. (JP) 2001-02-28 EP disclosed
EP-0945470-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 1999-09-29 EP disclosed