SCHEMBL78216

SCHEMBL78216

Cc1cc(C(C)(C)C)c(O[Al](CC(C)C)Oc2c(C(C)(C)C)cc(C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CA2 P00918 1/20 0.38
POLB P06746 1/20 0.38
TYR P14679 1/20 0.38
HSPA5 P11021 1/20 0.36
CYP2D6 P10635 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585549 0.86 SMN1; SMN2 (0.38) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL79258 0.81 CA2 (0.36) SMN1; SMN2ALDH1A1CA2
SCHEMBL937756 0.80 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL585179 0.79 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL6842753 0.79 NPC1 (0.33) CYP3A4
SCHEMBL25419233 0.77 ALDH1A1 (0.32) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL7153443 0.77 ALDH1A1 (0.32) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL3825880 0.75 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL77412 0.75 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL6574570 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192444-A (Meth) acrylic ester (co) polymerization method based on (non) biomass source under synergistic regulation of thiourea anions containing S negative nucleophilic centers and Lewis acid without hydrogen bond participation 青岛大学 2025-06-24 CN claimed
US-12281185-B2 Anionic polymerization process and polymer production method KURARAY CO., LTD. (JP) 2025-04-22 US claimed
EP-3845570-B1 ANIONIC POLYMERIZATION PROCESS AND POLYMER PRODUCTION METHOD KURARAY CO (JP) 2024-10-09 EP claimed
CN-117362482-A Polymerization catalyst composition, method for preparing block copolymer and application thereof 中国石油化工股份有限公司 2024-01-09 CN claimed
CN-115260353-B Acrylic ester polymerization reaction method based on synergistic regulation and control of hydrogen bond and Lewis acid 青岛大学 2023-08-15 CN claimed
CN-115260353-A Acrylate polymerization reaction method based on cooperative regulation and control of hydrogen bond and Lewis acid 青岛大学 2022-11-01 CN claimed
CN-112601765-B Anionic polymerization method and method for producing polymer 株式会社可乐丽 2022-10-25 CN claimed
CN-113736001-B Application of Lewis base, sorbate polymer and derivative thereof 吉林大学 2022-07-01 CN claimed
US-20210332163-A1 ANIONIC POLYMERIZATION PROCESS AND POLYMER PRODUCTION METHOD KURARAY CO., LTD. (JP) 2021-10-28 US claimed
EP-3845570-A1 ANIONIC POLYMERIZATION METHOD AND METHOD FOR PRODUCING POLYMER Kuraray Co., Ltd. (JP) 2021-07-07 EP claimed
EP-2099832-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS Albermarle Corporation (US) 2009-09-16 EP claimed
WO-2008076632-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-06-26 WO claimed
WO-2008036594-A2 CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS ALBEMARLE CORPORATION (US) 2008-03-27 WO claimed
US-6878789-B2 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 2005-04-12 US claimed
US-6831144-B2 Containing, in addition to an anionic polymerization initiator, a organoaluminum compound containing aryloxy groups, a Lewis base, and an ether or a tertiary amine KURARAY CO., LTD. (JP) 2004-12-14 US claimed
EP-0945470-B1 Preparation process of acrylic acid ester polymer KURARAY CO (JP) 2004-10-13 EP claimed
US-6767976-B2 POLYMERIZING METHACRYLIC ESTER OR ACRYLIC ESTER ANIONICALLY, USING A POLYMERIZATION INITIATOR COMPRISING ADDITION REACTION PRODUCT OF CONJUGATED DIENE COMPOUND AND ORGANIC ALKALI METAL COMPOUND AND TERTIARY ORGANOALUMINUM COMPOUND KURARAY CO., LTD. (JP) 2004-07-27 US claimed
US-20020032290-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 2002-03-14 US claimed
US-6329480-B1 POLYMERIZING ACRYLIC ACID ESTER, ACRYLIC/METHACRYLIC MONOMER PRESENCE OF AN ORGANOLITHIUM COMPOUND AND AN ORGANOALUMINUM COMPOUND TO FORM BLOCK COPOLYMER KURARAY CO., LTD. (JP) 2001-12-11 US claimed
EP-0945470-A1 Preparation process of acrylic acid ester polymer KURARAY CO., LTD. (JP) 1999-09-29 EP claimed