Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.69 |
| ▸ | PRKACG | P22612 | 1/20 | 0.69 |
| ▸ | PRKACB | P22694 | 1/20 | 0.69 |
| ▸ | PRKCB | P05771 | 18/20 | 0.64 |
| ▸ | PRKCA | P17252 | 12/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 9/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | JAK1 | P23458 | 1/20 | 0.53 |
| ▸ | TYK2 | P29597 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841273 | 0.90 | PRKCB (0.70) | PRKACAPRKACGPRKACBPRKCBPRKCA | |
| SCHEMBL7843953 | 0.84 | PRKCB (0.52) | PRKACAPRKACGPRKACBPRKCBPRKCA | |
| SCHEMBL7843706 | 0.84 | PRKCB (0.59) | PRKACAPRKACGPRKACBPRKCBPRKCA | |
| SCHEMBL7841836 | 0.84 | PRKCB (0.62) | PRKCBPRKCAPRKCEGSK3BJAK2 | |
| Hydrochloric Acid SCHEMBL7846140 | 0.83 | PRKCB (0.58) | PRKACAPRKACGPRKACBPRKCBPRKCA | |
| SCHEMBL7844621 | 0.81 | PRKCB (0.59) | PRKCBPRKCAPRKCEGSK3BJAK2 | |
| Hydrochloric Acid SCHEMBL7841120 | 0.79 | PRKCB (0.59) | PRKCBPRKCAPRKCEGSK3BJAK2 | |
| SCHEMBL7841465 | 0.78 | PRKCB (0.96) | PRKACAPRKACGPRKACBPRKCBPRKCA | |
| SCHEMBL7831659 | 0.78 | PRKCB (1.00) | PRKACAPRKACGPRKACBPRKCBPRKCA | |
| SCHEMBL7842209 | 0.78 | PRKCB (0.58) | PRKCBPRKCAPRKCEGSK3BJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | claimed |
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | disclosed |