Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 16/20 | 0.52 |
| ▸ | PRKCA | P17252 | 10/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | PRKACG | P22612 | 1/20 | 0.51 |
| ▸ | PRKACB | P22694 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843948 | 0.88 | PRKACA (0.54) | PRKCBPRKCAPRKCEPRKACAPRKACG | |
| SCHEMBL7832023 | 0.84 | PRKACA (0.69) | PRKCBPRKCAPRKCEPRKACAPRKACG | |
| SCHEMBL7844621 | 0.79 | PRKCB (0.59) | PRKCBPRKCAPRKCEGSK3B | |
| SCHEMBL7841273 | 0.78 | PRKCB (0.70) | PRKCBPRKCAPRKCEPRKACAPRKACG | |
| SCHEMBL7832859 | 0.78 | HTR6 (0.46) | PRKCBPRKCAPRKCEPRKACAPRKACG | |
| SCHEMBL7843706 | 0.77 | PRKCB (0.59) | PRKCBPRKCAPRKCEPRKACAPRKACG | |
| SCHEMBL7841836 | 0.76 | PRKCB (0.62) | PRKCBPRKCAPRKCEGSK3B | |
| Hydrochloric Acid SCHEMBL7841120 | 0.76 | PRKCB (0.59) | PRKCBPRKCAPRKCEGSK3B | |
| SCHEMBL7842723 | 0.74 | HTR6 (0.49) | BCHEHTR6 | |
| SCHEMBL7842209 | 0.73 | PRKCB (0.58) | PRKCBPRKCAPRKCEGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120414-A1 | DISUBSTITUTED MALEIMIDE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | JAPAN TOBACCO INC. (JP) | 2001-08-01 | — | — | EP | disclosed |