Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 9/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832034 | 1.00 | PRMT1 (0.62) | PRMT1MGLLFAAHNPSR1HSP90AA1 | |
| SCHEMBL8356354 | 0.80 | DDAH1 (0.55) | MGLLFAAHNPSR1HSP90AA1ALDH1A1 | |
| SCHEMBL8356254 | 0.80 | DDAH1 (0.55) | MGLLFAAHNPSR1HSP90AA1ALDH1A1 | |
| SCHEMBL8356258 | 0.80 | DDAH1 (0.55) | MGLLFAAHNPSR1HSP90AA1ALDH1A1 | |
| SCHEMBL9305974 | 0.79 | PRMT1 (0.59) | PRMT1NPSR1ALDH1A1PKMHDAC3 | |
| SCHEMBL9305975 | 0.79 | PRMT1 (0.59) | PRMT1NPSR1ALDH1A1PKMHDAC3 | |
| Maleic Acid SCHEMBL28132961 | 0.78 | MGLL (0.72) | MGLLFAAHNPSR1HSP90AA1ALDH1A1 | |
| SCHEMBL10416057 | 0.78 | PRMT1 (0.61) | PRMT1NPSR1ALDH1A1PKMHDAC3 | |
| SCHEMBL10416055 | 0.78 | PRMT1 (0.61) | PRMT1NPSR1ALDH1A1PKMHDAC3 | |
| SCHEMBL271386 | 0.77 | NPSR1 (0.74) | PRMT1NPSR1ALDH1A1PKMHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877204-A | Compounds containing a michael-acceptor, especially maleimide or maleic acid derivatives, directly or indirectly linked to a chromophore and their use in long lasting sunscreen compositions | VANGUARD MEDICA LIMITED (GB) | 1999-03-02 | — | — | US | claimed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |