Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656041 | 0.87 | PTPN1 (0.60) | PTPN1 | |
| SCHEMBL7502882 | 0.86 | PTPN1 (0.82) | PTPN1 | |
| SCHEMBL7502371 | 0.81 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7504516 | 0.77 | PTPN1 (0.65) | PTPN1 | |
| SCHEMBL7686456 | 0.76 | PTPN1 (0.71) | PTPN1 | |
| SCHEMBL7504179 | 0.76 | PTPN1 (0.64) | PTPN1 | |
| SCHEMBL7495356 | 0.74 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7501700 | 0.72 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7688165 | 0.72 | PTPN1 (0.78) | PTPN1 | |
| SCHEMBL7496706 | 0.69 | PTPN1 (0.67) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010053785-A1 | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | WYETH | 2001-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053785-A1 | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | GPR119, INSR, IAPP | PTPN1 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.