Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.35 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835684 | 0.85 | ITGB3 (0.48) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL6779388 | 0.82 | ITGB3 (0.55) | ITGB3ITGA2BITGAV | |
| SCHEMBL7836730 | 0.82 | ITGB3 (0.40) | ITGB3ITGA2BPARP1PARP10ITGAV | |
| SCHEMBL7837230 | 0.78 | ITGB3 (0.49) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL7836410 | 0.78 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGAVITGA5 | |
| SCHEMBL7832124 | 0.77 | ITGB3 (0.48) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL7836585 | 0.77 | ITGB3 (0.47) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL7836000 | 0.75 | ITGB3 (0.48) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL7832113 | 0.74 | ITGB3 (0.44) | ITGB3ITGA2BITGAV | |
| SCHEMBL6984586 | 0.74 | ITGB3 (0.65) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-B1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2001-07-18 | — | — | EP | claimed |