Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 7/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835684 | 0.86 | ITGB3 (0.48) | ITGB3ITGAV | |
| SCHEMBL6777398 | 0.82 | SUCNR1 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL7832112 | 0.82 | ITGB3 (0.41) | ITGB3ITGA2BCTSAPARP1PARP10 | |
| SCHEMBL7837230 | 0.79 | ITGB3 (0.49) | ITGB3ITGAV | |
| SCHEMBL7836585 | 0.78 | ITGB3 (0.47) | ITGB3ITGAV | |
| SCHEMBL7832124 | 0.78 | ITGB3 (0.48) | ITGB3ITGAV | |
| SCHEMBL7836410 | 0.77 | ITGB3 (0.44) | ITGB3ITGA2BCTSAITGAV | |
| SCHEMBL7836000 | 0.76 | ITGB3 (0.48) | ITGB3ITGAV | |
| SCHEMBL7372605 | 0.74 | ITGB3 (0.51) | ITGB3ITGA2BCTSAPARP1PARP10 | |
| SCHEMBL7836399 | 0.74 | GPR139 (0.48) | ITGB3ITGAVALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-B1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2001-07-18 | — | — | EP | claimed |