Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 10/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6159015 | 0.99 | KDM4E (0.38) | MEN1BLMKMT2AKDM4ELMNA | |
| SCHEMBL7000651 | 0.92 | MEN1 (0.37) | MEN1BLMKMT2AKDM4ELMNA | |
| SCHEMBL4591366 | 0.91 | KCNH3 (0.37) | MEN1BLMKMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6991716 | 0.91 | KDM4E (0.38) | MEN1BLMKMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6968110 | 0.91 | KCNH3 (0.39) | MEN1BLMKMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6965281 | 0.89 | KCNH3 (0.40) | MEN1BLMKMT2AKDM4ELMNA | |
| Revaprazan SCHEMBL2194461 | 0.88 | MEN1 (0.40) | MEN1BLMKMT2AKDM4ELMNA | |
| Revaprazan SCHEMBL6990999 | 0.88 | MEN1 (0.40) | MEN1BLMKMT2AKDM4ELMNA | |
| Revaprazan SCHEMBL6993033 | 0.88 | MEN1 (0.40) | MEN1BLMKMT2AKDM4ELMNA | |
| Revaprazan SCHEMBL29388090 | 0.88 | MEN1 (0.40) | MEN1BLMKMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |