Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832305 | 1.00 | OPRK1 (0.34) | OPRK1RXFP1KDM4EHPGDCYP2C19 | |
| SCHEMBL7832312 | 1.00 | OPRK1 (0.34) | OPRK1RXFP1KDM4EHPGDCYP2C19 | |
| SCHEMBL7835604 | 0.92 | HTR3A (0.32) | KMT2AMEN1LMNARETHTR3A | |
| SCHEMBL7835607 | 0.92 | HTR3A (0.32) | KMT2AMEN1LMNARETHTR3A | |
| SCHEMBL7835615 | 0.92 | HTR3A (0.32) | KMT2AMEN1LMNARETHTR3A | |
| SCHEMBL7823053 | 0.90 | OPRK1 (0.32) | OPRK1RXFP1KDM4EHPGDCYP2C19 | |
| SCHEMBL708977 | 0.89 | RXFP1 (0.37) | OPRK1RXFP1KDM4EHPGDCYP2C19 | |
| SCHEMBL7831785 | 0.89 | RXFP1 (0.37) | OPRK1RXFP1KDM4EHPGDCYP2C19 | |
| SCHEMBL7831769 | 0.89 | RXFP1 (0.37) | OPRK1RXFP1KDM4EHPGDCYP2C19 | |
| SCHEMBL8802441 | 0.87 | RET (0.31) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787726-B1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-0787726-A1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |