SCHEMBL7832375

SCHEMBL7832375

O=C(O)CC(CC(=O)OC(=O)CC(CC(=O)O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8877183 0.86 SLC22A6 (0.43) SLC22A6TDP1SMN1; SMN2
SCHEMBL8877041 0.83 SLC22A6 (0.31) SLC22A6TDP1
SCHEMBL27383612 0.80 GAA (0.40) TDP1
SCHEMBL8668660 0.76 MMP1 (0.36) SLC22A6
SCHEMBL27306328 0.76 SLC22A6 (0.35) SLC22A6TDP1SMN1; SMN2
SCHEMBL28006567 0.75 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2
SCHEMBL27464365 0.75 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2
SCHEMBL28474842 0.73 GABRR1 (0.46) SLC22A6TDP1SMN1; SMN2
SCHEMBL1604218 0.73 SLC22A6 (0.36) SLC22A6TDP1SMN1; SMN2
SCHEMBL22118498 0.72 HTT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563384-B1 URACIL DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-10-04 EP disclosed
US-5631209-A ALGICIDES ROHM AND HAAS COMPANY (US) 1997-05-20 US disclosed
US-5502027-A ALGICIDES ROHM AND HAAS COMPANY (US) 1996-03-26 US disclosed
EP-0415642-B1 Glutarimides ROHM & HAAS (US) 1995-12-06 EP disclosed
US-5393735-A N-(halo-oxy-)phenyl substituted cyclic imides ROHM AND HAAS COMPANY (US) 1995-02-28 US disclosed
US-5356863-A Herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-18 US disclosed
EP-0415641-B1 Substituted glutaramic acids and derivatives ROHM & HAAS (US) 1994-01-19 EP disclosed
EP-0563384-A1 URACIL DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-10-06 EP disclosed
US-5238908-A HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES ROHM AND HAAS COMPANY (US) 1993-08-24 US disclosed
WO-1993005037-A1 OXETANE AND THIAETANE DERIVATIVES CIBA-GEIGY AG (CH) 1993-03-18 WO disclosed
EP-0530642-A1 Herbicidal oxetane and thiaetane derivatives CIBA-GEIGY AG (CH) 1993-03-10 EP disclosed
US-5180418-A HERBICIDALLY ACTIVE THIADIAZABICYCLONONANES AND NONENES CIBA-GEIGY CORPORATION (US) 1993-01-19 US disclosed
EP-0454444-A1 Glutarimide derivatives and herbicides NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-10-30 EP disclosed
EP-0415641-A1 Substituted glutaramic acids and derivatives ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed