SCHEMBL7832377

SCHEMBL7832377

O=C1CC(C(F)(F)F)CC(=O)O1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8877047 0.80 TSHR (0.33) TSHR
SCHEMBL10338677 0.75 HTT (0.31)
SCHEMBL15187638 0.74 ALDH1A1 (0.37) TSHRSMN1; SMN2
SCHEMBL1711546 0.70 MAPT (0.34) NOS3NOS1NOS2
SCHEMBL12086395 0.70
SCHEMBL18603970 0.70
SCHEMBL24623985 0.69
SCHEMBL11955386 0.67 TSHR (0.47) TSHRSMN1; SMN2
SCHEMBL12326723 0.65 NOS3 (0.32) NOS3NOS1NOS2
SCHEMBL14551907 0.65 NOS3 (0.32) NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220223914-A1 ELECTROLYTE, ELECTROCHEMICAL DEVICE, AND ELECTRONIC DEVICE NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2022-07-14 US disclosed
EP-0563384-B1 URACIL DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-10-04 EP disclosed
CN-1036564-C Herbicidal glutarmides ROHM & HAAS (US) 1997-12-03 CN disclosed
US-5631209-A ALGICIDES ROHM AND HAAS COMPANY (US) 1997-05-20 US disclosed
US-5502027-A ALGICIDES ROHM AND HAAS COMPANY (US) 1996-03-26 US disclosed
EP-0415642-B1 Glutarimides ROHM & HAAS (US) 1995-12-06 EP disclosed
US-5393735-A N-(halo-oxy-)phenyl substituted cyclic imides ROHM AND HAAS COMPANY (US) 1995-02-28 US disclosed
US-5356863-A Herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-18 US disclosed
EP-0415641-B1 Substituted glutaramic acids and derivatives ROHM & HAAS (US) 1994-01-19 EP disclosed
EP-0563384-A1 URACIL DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1993-10-06 EP disclosed
US-5238908-A HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES ROHM AND HAAS COMPANY (US) 1993-08-24 US disclosed
WO-1993005037-A1 OXETANE AND THIAETANE DERIVATIVES CIBA-GEIGY AG (CH) 1993-03-18 WO disclosed
EP-0530642-A1 Herbicidal oxetane and thiaetane derivatives CIBA-GEIGY AG (CH) 1993-03-10 EP disclosed
US-5180418-A HERBICIDALLY ACTIVE THIADIAZABICYCLONONANES AND NONENES CIBA-GEIGY CORPORATION (US) 1993-01-19 US disclosed
EP-0468924-A2 New herbicides CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed
EP-0454444-A1 Glutarimide derivatives and herbicides NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-10-30 EP disclosed
CN-1049770-A Weeding glutaramic acid and its derivative ROHM & HAAS (US) 1991-03-13 CN disclosed
EP-0415641-A1 Substituted glutaramic acids and derivatives ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed