Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | PYGB | P11216 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ITPR3 | Q14573 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899187 | 0.81 | ADORA1 (0.38) | LGALS8SMPD1ADORA1ITPR3 | |
| SCHEMBL31207057 | 0.79 | PYGB (0.51) | PYGB | |
| SCHEMBL14940452 | 0.78 | PYGB (0.54) | PYGB | |
| SCHEMBL16256436 | 0.78 | PYGB (0.54) | PYGB | |
| SCHEMBL28589455 | 0.78 | PYGB (0.54) | PYGB | |
| SCHEMBL94835 | 0.77 | PYGB (0.44) | PYGB | |
| SCHEMBL4596697 | 0.76 | SMPD1 (0.48) | SMPD1ITPR3 | |
| SCHEMBL5378658 | 0.76 | SMPD1 (0.48) | SMPD1ITPR3 | |
| SCHEMBL4595256 | 0.76 | SMPD1 (0.48) | SMPD1ITPR3 | |
| SCHEMBL30237668 | 0.76 | SMPD1 (0.54) | SMPD1ITPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160259883-A1 | SENSE-ANTISENSE GENE PAIRS FOR PATIENT STRATIFICATION, PROGNOSIS, AND THERAPEUTIC BIOMARKERS IDENTIFICATION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-09-08 | — | — | US | disclosed |
| US-20120072124-A1 | GENES ASSOCIATED WITH PROGRESSION AND RESPONSE IN CHRONIC MYELOID LEUKEMIA AND USES THEREOF | ROSETTA INPHARMATICS, LLC | 2012-03-22 | — | — | US | disclosed |
| US-20110172107-A1 | ASSAY FOR IDENTIFYING AGENTS THAT MODULATE EPIGENETIC SILENCING, AND AGENTS IDENTIFIED THEREBY | FOX CHASE CANCER CENTER (US) | 2011-07-14 | — | — | US | disclosed |
| WO-2010017526-A1 | PURINE NUCLEOTIDES ISOTOPICALLY LABELED IN THE PURINE BASE, METHODS OF MAKING THEREOF AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-11 | — | — | WO | disclosed |