Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242347 | 0.88 | GAA (0.49) | GAANR4A2KDM4EALDH1A1LMNA | |
| SCHEMBL6631783 | 0.83 | NGFR (0.43) | GAANR4A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL7835698 | 0.83 | GAA (0.76) | GAAHSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3385819 | 0.82 | GAA (0.66) | GAAHSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14487045 | 0.79 | EGFR (0.67) | GAAHSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30608287 | 0.79 | EGFR (0.67) | GAAHSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6634172 | 0.79 | MAPT (0.56) | GAAHTR6TDP1KDM4EMEN1 | |
| SCHEMBL7838122 | 0.79 | ALDH1A1 (0.47) | GAAHTR1DNR4A2KDM4EMEN1 | |
| SCHEMBL17357055 | 0.78 | GAA (0.69) | GAAHSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11790716 | 0.78 | GAA (0.68) | GAAHSD17B10NR4A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144415-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042045-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |