Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | F9 | P00740 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832698 | 0.91 | F9 (0.42) | CBFBFGFR1FLT1F9NCOA3 | |
| Hydrochloric Acid SCHEMBL8155241 | 0.78 | CBFB (0.55) | CBFBFGFR1FLT1F9NCOA3 | |
| SCHEMBL7834506 | 0.76 | CBFB (0.53) | CBFBFGFR1FLT1F9NCOA3 | |
| SCHEMBL7407358 | 0.76 | CBFB (0.50) | CBFBFGFR1FLT1F9NCOA3 | |
| SCHEMBL7834250 | 0.75 | CBFB (0.52) | CBFBFGFR1FLT1F9NCOA3 | |
| SCHEMBL7821991 | 0.73 | NPC1 (0.55) | CBFBFGFR1FLT1F9NCOA3 | |
| SCHEMBL7822772 | 0.73 | CBFB (0.55) | CBFBFGFR1FLT1F9NCOA3 | |
| SCHEMBL7821732 | 0.73 | RAB9A (0.58) | CBFBFGFR1FLT1NCOA3CYP19A1 | |
| SCHEMBL7833754 | 0.72 | CBFB (0.54) | CBFBFGFR1FLT1F9NCOA3 | |
| Hydrochloric Acid SCHEMBL8159913 | 0.72 | RAB9A (0.57) | CBFBFGFR1FLT1NCOA3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |