Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832698 | 0.83 | F9 (0.42) | CBFBFGFR1FLT1CYP11B1CYP11B2 | |
| SCHEMBL7406624 | 0.82 | CBFB (0.43) | CBFBFGFR1FLT1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8155236 | 0.82 | F9 (0.46) | CBFBFGFR1FLT1CYP11B1CYP11B2 | |
| SCHEMBL7406663 | 0.82 | F10 (0.54) | F2F10F7F9 | |
| SCHEMBL7822768 | 0.81 | IDH1 (0.48) | CBFBFGFR1FLT1CYP11B1CYP11B2 | |
| SCHEMBL7821986 | 0.81 | NPC1 (0.55) | CBFBFGFR1FLT1CYP11B1CYP11B2 | |
| SCHEMBL7821729 | 0.81 | RAB9A (0.55) | CBFBCYP11B1CYP11B2CYP19A1GAA | |
| SCHEMBL7833749 | 0.80 | MEN1 (0.46) | CBFBFGFR1FLT1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8159907 | 0.80 | RAB9A (0.54) | CBFBCYP11B1CYP11B2CYP19A1GAA | |
| Hydrochloric Acid SCHEMBL8155587 | 0.80 | NPC1 (0.54) | CBFBFGFR1FLT1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | claimed |