Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833044 | 0.92 | CBFB (0.52) | CBFBNCOA3F9ENPP2MKNK1 | |
| SCHEMBL7837220 | 0.91 | NPC1 (0.43) | CBFBNCOA3F9ENPP2MKNK1 | |
| SCHEMBL7834174 | 0.87 | F9 (0.44) | CBFBNCOA3F9CYP11B1CYP11B2 | |
| SCHEMBL7832653 | 0.87 | F9 (0.44) | CBFBNCOA3F9CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8155873 | 0.86 | F9 (0.44) | CBFBNCOA3F9CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8157010 | 0.86 | F9 (0.44) | CBFBNCOA3F9CYP11B1CYP11B2 | |
| SCHEMBL7830706 | 0.85 | NPC1 (0.46) | CBFBNCOA3F9CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7821793 | 0.85 | NPC1 (0.46) | CBFBNCOA3F9CYP11B1CYP11B2 | |
| SCHEMBL7832658 | 0.85 | NPC1 (0.40) | CBFBNCOA3F9CYP11B1CYP11B2 | |
| SCHEMBL7834713 | 0.85 | ALOX15 (0.44) | CBFBNCOA3F9CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| US-6040327-A | INHIBITORS OF INTERLEUKINS; TREATING RHEUMATOID ARTHRITIS OR ARTHROSIS | ADIR ET COMPAGNIE (FR) | 2000-03-21 | — | — | US | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |