Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8159109 | 0.99 | MAOA (0.48) | MAOAMAOBKDM4EGAACYP11B1 | |
| SCHEMBL7833328 | 0.92 | MAOA (0.52) | MAOAMAOBKDM4EGAACYP11B1 | |
| Hydrochloric Acid SCHEMBL8159112 | 0.91 | MAOA (0.51) | MAOAMAOBKDM4EGAACYP11B1 | |
| SCHEMBL7840878 | 0.89 | MAOA (0.45) | MAOAMAOBKDM4EGAACYP11B1 | |
| SCHEMBL7821973 | 0.86 | MAOA (0.43) | MAOAMAOBKDM4EGAACYP11B1 | |
| SCHEMBL7836267 | 0.85 | MAOA (0.42) | MAOAMAOBKDM4EGAACYP11B1 | |
| SCHEMBL7821986 | 0.82 | NPC1 (0.55) | MAOAMAOBKDM4ECYP11B1CYP11B2 | |
| SCHEMBL7834574 | 0.82 | CYP11B1 (0.51) | MAOAMAOBCYP11B1CYP11B2LMNA | |
| SCHEMBL7833472 | 0.82 | CBFB (0.39) | MAOAMAOBCYP11B1CYP11B2LMNA | |
| Hydrochloric Acid SCHEMBL8155587 | 0.81 | NPC1 (0.54) | MAOAMAOBKDM4ECYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |