Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272766 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ALOX15KMT2ASMN1; SMN2CA12 | |
| SCHEMBL11813187 | 0.82 | KEAP1 (0.42) | ALDH1A1ALOX15KMT2AHPGDMAPT | |
| SCHEMBL11826431 | 0.82 | CSNK2A1 (0.44) | ALDH1A1KMT2ATSHRPOLBAKR1C3 | |
| SCHEMBL11414000 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALOX15KMT2ASMN1; SMN2CA12 | |
| SCHEMBL9171525 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALOX15KMT2ASMN1; SMN2TSHR | |
| SCHEMBL6234867 | 0.80 | ALDH1A1 (0.45) | ALDH1A1ALOX15KMT2ASMN1; SMN2CA12 | |
| SCHEMBL11821337 | 0.79 | KMT2A (0.44) | ALDH1A1ALOX15KMT2ASMN1; SMN2TSHR | |
| SCHEMBL7764260 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ALOX15KMT2ASMN1; SMN2CA12 | |
| SCHEMBL30828909 | 0.78 | ALDH1A1 (0.56) | ALDH1A1ALOX15SMN1; SMN2TSHRCA12 | |
| SCHEMBL2573164 | 0.78 | ALDH1A1 (0.56) | ALDH1A1ALOX15SMN1; SMN2TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |