Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833472 | 0.92 | CBFB (0.39) | CBFBFGFR1FLT1NCOA3MAOB | |
| SCHEMBL7840889 | 0.90 | MAOA (0.48) | CBFBFGFR1FLT1NCOA3MAOB | |
| SCHEMBL7833198 | 0.85 | CBFB (0.49) | CBFBFGFR1FLT1NCOA3MAOB | |
| SCHEMBL7821975 | 0.85 | MAOA (0.45) | CBFBFGFR1FLT1NCOA3MAOB | |
| SCHEMBL7832662 | 0.84 | CBFB (0.49) | CBFBFGFR1FLT1NCOA3MAOB | |
| SCHEMBL7836269 | 0.84 | MAOA (0.44) | CBFBFGFR1FLT1NCOA3MAOB | |
| Hydrochloric Acid SCHEMBL7830602 | 0.84 | CBFB (0.48) | CBFBFGFR1FLT1NCOA3MAOB | |
| SCHEMBL7833722 | 0.83 | CBFB (0.49) | CBFBFGFR1FLT1NCOA3MAOB | |
| SCHEMBL7831676 | 0.83 | CBFB (0.48) | CBFBFGFR1FLT1NCOA3MAOB | |
| SCHEMBL7832812 | 0.83 | CBFB (0.48) | CBFBFGFR1FLT1NCOA3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |