Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833717 | 0.92 | F9 (0.41) | CBFBFGFR1FLT1NCOA3F9 | |
| SCHEMBL7836269 | 0.91 | MAOA (0.44) | CBFBFGFR1FLT1NCOA3F9 | |
| SCHEMBL7833198 | 0.87 | CBFB (0.49) | CBFBFGFR1FLT1NCOA3F9 | |
| Hydrochloric Acid SCHEMBL7830602 | 0.86 | CBFB (0.48) | CBFBFGFR1FLT1NCOA3F9 | |
| SCHEMBL7840889 | 0.85 | MAOA (0.48) | CBFBFGFR1FLT1NCOA3F9 | |
| SCHEMBL7832392 | 0.84 | CBFB (0.47) | CBFBFGFR1FLT1NCOA3F9 | |
| SCHEMBL7821991 | 0.84 | NPC1 (0.55) | CBFBFGFR1FLT1NCOA3F9 | |
| SCHEMBL7833478 | 0.83 | CBFB (0.48) | CBFBFGFR1FLT1NCOA3F9 | |
| Hydrochloric Acid SCHEMBL8155594 | 0.83 | NPC1 (0.54) | CBFBFGFR1FLT1NCOA3F9 | |
| SCHEMBL7836267 | 0.83 | MAOA (0.42) | CBFBNCOA3F9CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| US-6040327-A | INHIBITORS OF INTERLEUKINS; TREATING RHEUMATOID ARTHRITIS OR ARTHROSIS | ADIR ET COMPAGNIE (FR) | 2000-03-21 | — | — | US | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |