Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822808 | 0.90 | KMT2A (0.39) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL194042 | 0.89 | EPHA2 (0.37) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL3025485 | 0.89 | EPHA2 (0.37) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL15802906 | 0.88 | EPHA2 (0.36) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7840397 | 0.87 | EPHA2 (0.37) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL12458892 | 0.86 | EPHA2 (0.35) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL16910352 | 0.85 | EPHA2 (0.35) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL196374 | 0.85 | EPHA2 (0.35) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL196264 | 0.85 | EPHA2 (0.35) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL761081 | 0.85 | LMNA (0.38) | EPHA2FLT4GSK3BRARBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787726-B1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| CN-1053668-C | Novel compound, process for producing the same, and antitumor agent | DAINIPPON PHARMACEUTICAL CO (JP) | 2000-06-21 | — | — | CN | disclosed |
| US-5817669-A | A COMPOUND CONTAINING 1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| CN-1158614-A | Novel compound, process for producing the same, and antitumor agent | DAINIPPON PHARMACEUTICAL CO (JP) | 1997-09-03 | — | — | CN | disclosed |
| EP-0787726-A1 | NOVEL COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTITUMOR AGENT | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |