Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | ME2 | P23368 | 2/20 | 0.36 |
| ▸ | ME1 | P48163 | 2/20 | 0.36 |
| ▸ | ME3 | Q16798 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501796 | 0.87 | MAPT (0.64) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL14764336 | 0.86 | MAPT (0.65) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9665897 | 0.85 | MAPT (0.65) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8504055 | 0.85 | MAPT (0.57) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL7834004 | 0.83 | MAPT (0.61) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL7834002 | 0.83 | MAPT (0.61) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9665027 | 0.83 | MAPT (0.62) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9279160 | 0.81 | MAPT (0.60) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9666082 | 0.80 | MAPT (0.62) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL9666033 | 0.80 | MAPT (0.59) | MAPTKDM4ELMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010039281-A1 | Amino acid ester containing azole antifungals | MEERPOEL LIEVEN (BE) | 2001-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039281-A1 | Amino acid ester containing azole antifungals | DAO, SLC7A1, IL4I1 | MAPT 3961/4885KDM4E 1361/4885LMNA 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.