Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18856930 | 0.89 | MAPT (0.64) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL7834009 | 0.87 | MAPT (0.64) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL14764626 | 0.86 | MAPT (0.66) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL11074635 | 0.85 | MAPT (0.67) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL11069441 | 0.82 | MAPT (0.64) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL7662521 | 0.82 | MAPT (0.61) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL13499379 | 0.81 | MAPT (0.60) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL15912699 | 0.81 | MAPT (0.61) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL9384752 | 0.81 | MAPT (0.58) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL7451368 | 0.81 | MAPT (0.58) | MAPTALDH1A1KDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958289-A1 | AMINO ACID ESTER CONTAINING AZOLE ANTIFUNGALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998034934-A1 | AMINO ACID ESTER CONTAINING AZOLE ANTIFUNGALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-08-13 | — | — | WO | disclosed |