Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | BRS3 | P32247 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8149767 | 0.99 | USP2 (0.54) | MEN1USP2MAPTKMT2AHSD17B10 | |
| SCHEMBL7834232 | 0.92 | RAB9A (0.47) | MEN1USP2MAPTKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL8149760 | 0.91 | RAB9A (0.47) | MEN1USP2MAPTKMT2AHSD17B10 | |
| SCHEMBL7834561 | 0.86 | RAB9A (0.56) | MEN1KMT2ABRS3RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8149755 | 0.85 | RAB9A (0.55) | MEN1KMT2ABRS3RAB9ANPC1 | |
| SCHEMBL7834178 | 0.83 | CBFB (0.52) | MEN1USP2MAPTKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL8157014 | 0.82 | CBFB (0.51) | BRS3RAB9ANPC1CBFBF9 | |
| SCHEMBL7821732 | 0.80 | RAB9A (0.58) | MEN1KMT2ARAB9ANPC1CBFB | |
| Hydrochloric Acid SCHEMBL8159913 | 0.79 | RAB9A (0.57) | MEN1KMT2ARAB9ANPC1CBFB | |
| SCHEMBL7836455 | 0.79 | CBFB (0.52) | MEN1MAPTKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |