Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8149760 | 0.99 | RAB9A (0.47) | RAB9ANPC1USP2MEN1MAPT | |
| SCHEMBL7834239 | 0.92 | MEN1 (0.55) | RAB9ANPC1USP2MEN1MAPT | |
| Hydrochloric Acid SCHEMBL8149767 | 0.91 | USP2 (0.54) | RAB9ANPC1USP2MEN1MAPT | |
| SCHEMBL7834555 | 0.86 | RAB9A (0.55) | RAB9ANPC1MEN1KMT2AF9 | |
| Hydrochloric Acid SCHEMBL8149742 | 0.85 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2AF9 | |
| SCHEMBL7834174 | 0.83 | F9 (0.44) | RAB9ANPC1MAPTF9IDH1 | |
| Hydrochloric Acid SCHEMBL8157010 | 0.82 | F9 (0.44) | RAB9ANPC1MAPTF9IDH1 | |
| SCHEMBL7821729 | 0.80 | RAB9A (0.55) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8159907 | 0.79 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7836452 | 0.79 | MAOA (0.44) | RAB9ANPC1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |