Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901695 | 0.63 | TSHR (0.32) | TSHR | |
| SCHEMBL367457 | 0.62 | TSHR (0.52) | TSHRHSD17B10LMNA | |
| SCHEMBL17294184 | 0.60 | TSHR (0.50) | TSHRHSD17B10LMNA | |
| SCHEMBL21767 | 0.58 | — | — | |
| SCHEMBL6100849 | 0.58 | — | — | |
| SCHEMBL8110002 | 0.58 | — | — | |
| SCHEMBL11579920 | 0.58 | — | — | |
| SCHEMBL249514 | 0.57 | TSHR (0.52) | TSHRHSD17B10LMNA | |
| SCHEMBL1567354 | 0.57 | TSHR (0.35) | TSHR | |
| SCHEMBL133284 | 0.56 | HSD17B10 (0.39) | TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748800-B1 | Pyrimidinedione, pyrimidinetrione, triazinedione derivatives as alpha-1-adrenergic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2001-05-09 | — | — | EP | disclosed |