Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | FNTA | P49354 | 12/20 | 0.41 |
| ▸ | FNTB | P49356 | 12/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826548 | 0.87 | FNTA (0.44) | CYP19A1FNTAFNTBPGGT1BCPA1 | |
| Hydrochloric Acid SCHEMBL7834168 | 0.86 | FNTA (0.44) | CYP19A1FNTAFNTBPGGT1BCPA1 | |
| SCHEMBL7845880 | 0.81 | FNTA (0.49) | CYP19A1FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7840097 | 0.80 | FNTA (0.48) | CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL7850296 | 0.79 | HRH3 (0.40) | CYP19A1FNTAFNTBPGGT1BCPA1 | |
| Hydrochloric Acid SCHEMBL7837018 | 0.76 | CYP19A1 (0.37) | CYP19A1FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL3845496 | 0.76 | FNTA (0.53) | CYP19A1FNTAFNTBPGGT1BKCNH2 | |
| Hydrochloric Acid SCHEMBL7528885 | 0.75 | FNTA (0.53) | CYP19A1FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL5552211 | 0.72 | HRH3 (0.41) | CYP19A1FNTAFNTBPGGT1BCPA1 | |
| SCHEMBL7452182 | 0.72 | OPRD1 (0.50) | CYP19A1KCNH2CPA1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891349-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-01-24 | — | — | EP | claimed |
| EP-0891349-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036888-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0891349-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-0891349-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036888-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |