Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820552 | 0.91 | CNR2 (0.41) | CNR1CNR2CASRL3MBTL1PLA2G1B | |
| SCHEMBL5448847 | 0.91 | TBXA2R (0.48) | TBXA2RTBXAS1CYP2C9 | |
| SCHEMBL5448839 | 0.91 | TBXA2R (0.48) | TBXA2RTBXAS1CYP2C9 | |
| SCHEMBL7833310 | 0.85 | LTB4R (0.41) | TBXA2RTBXAS1PDE4BCNR1CNR2 | |
| SCHEMBL12761962 | 0.84 | CYP2C9 (0.46) | CNR1CNR2L3MBTL1PLA2G1BATG4B | |
| SCHEMBL9310437 | 0.83 | TBXA2R (0.54) | TBXA2RTBXAS1CYP2C9 | |
| SCHEMBL7829250 | 0.82 | TBXA2R (0.40) | TBXA2RCNR1CNR2LMNACYP1A2 | |
| SCHEMBL9308388 | 0.82 | TBXA2R (0.56) | TBXA2RTBXAS1CYP2C9 | |
| SCHEMBL9391332 | 0.80 | PDE4B (0.57) | TBXA2RTBXAS1PDE4BCNR1CNR2 | |
| SCHEMBL9310060 | 0.79 | TBXA2R (0.49) | TBXA2RTBXAS1PDE4BCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |