Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310437 | 0.96 | TBXA2R (0.54) | TBXA2RTBXAS1CYP2C9BRD4BRD2 | |
| SCHEMBL9308388 | 0.95 | TBXA2R (0.56) | TBXA2RTBXAS1CYP2C9IMPDH1 | |
| SCHEMBL9549853 | 0.87 | TBXAS1 (0.56) | TBXA2RTBXAS1 | |
| SCHEMBL9307992 | 0.85 | TBXA2R (0.46) | TBXA2RTBXAS1CYP2C9LMNA | |
| SCHEMBL9310772 | 0.85 | HTR2A (0.36) | TBXA2RCYP2C9BRD4BRD2BRD3 | |
| SCHEMBL9549822 | 0.83 | TBXAS1 (0.61) | TBXA2RTBXAS1 | |
| SCHEMBL9662366 | 0.83 | SIGMAR1 (0.38) | TBXA2RCYP2C9MTNR1AMTNR1BMEN1 | |
| SCHEMBL9310821 | 0.83 | HRH1 (0.37) | TBXA2RCYP2C9MTNR1AMTNR1BCNR2 | |
| SCHEMBL9549642 | 0.82 | TBXAS1 (0.63) | TBXA2RTBXAS1 | |
| SCHEMBL9549707 | 0.82 | TBXAS1 (0.63) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |