Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402369 | 0.72 | PRMT5 (0.39) | NPC1PRMT5 | |
| SCHEMBL2402419 | 0.72 | PRMT5 (0.46) | TLR8TLR7NPC1PRMT5 | |
| SCHEMBL1528010 | 0.68 | TLR8 (0.69) | TLR8TLR7PRMT5 | |
| SCHEMBL5765345 | 0.68 | TLR8 (0.48) | TLR8TLR7NPC1PRMT5PDE10A | |
| SCHEMBL6801104 | 0.66 | TLR8 (0.41) | TLR8TLR7PDE4APDE4BPDE4C | |
| SCHEMBL3351060 | 0.66 | TLR8 (0.44) | TLR8TLR7PRMT5 | |
| SCHEMBL8582607 | 0.66 | L3MBTL1 (0.43) | NPC1 | |
| Ammonia Solution, Strong SCHEMBL28841614 | 0.65 | L3MBTL1 (0.42) | NPC1 | |
| Bromide SCHEMBL28285568 | 0.65 | L3MBTL1 (0.42) | NPC1 | |
| SCHEMBL9844319 | 0.64 | PARP1 (0.63) | TLR8TLR7PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100802-A1 | OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF | 3M Innovative Properties Company (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006577-A1 | OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |