Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832001 | 0.84 | ALOX5 (0.57) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7823354 | 0.83 | ALOX5 (0.56) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7832879 | 0.82 | ALOX5 (0.54) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7833693 | 0.81 | MAPT (0.52) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7834393 | 0.79 | MAPT (0.54) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7823567 | 0.77 | MAPT (0.52) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6315808 | 0.76 | GAA (0.74) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL10909908 | 0.75 | ALOX5 (0.45) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7832442 | 0.75 | RAB9A (0.47) | ALOX5KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL22548001 | 0.73 | RAB9A (0.72) | KMT2AMAPTMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144415-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042045-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |