SCHEMBL7835313

SCHEMBL7835313

O=C(O)CSC1CCOC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28924613 0.83
SCHEMBL31631322 0.75
SCHEMBL997207 0.75 CYP2D6 (0.43) CYP2D6CYP2C19HIF1A
SCHEMBL9517288 0.73
SCHEMBL3706423 0.72 KMT2A (0.43) CYP2D6CYP2C19HIF1A
SCHEMBL4202744 0.71
SCHEMBL28862942 0.71 POLB (0.31)
SCHEMBL11667152 0.70
SCHEMBL24564744 0.70 KMT2A (0.46) CYP2D6CYP2C19HIF1A
SCHEMBL1200818 0.70 KMT2A (0.46) CYP2D6CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563878-B1 Process for producing 4-substituted azetidinone derivatives SUNTORY LTD (JP) 2001-08-29 EP disclosed
US-5808055-A Copper catalyzed process for producing 4-substituted azetidinone derivatives SUNTORY LIMITED (JP) 1998-09-15 US disclosed
EP-0273747-B1 Penem derivatives, production and use thereof SUNTORY LTD (JP) 1994-12-07 EP disclosed
EP-0563878-A2 Process for producing 4-substituted azetidinone derivatives SUNTORY LIMITED (JP) 1993-10-06 EP disclosed
US-5116832-A Penicillins substituted with heterocyclic oxygen ring SUNTORY LIMITED (JP) 1992-05-26 US disclosed
EP-0273747-A1 Penem derivatives, production and use thereof SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1988-07-06 EP disclosed