Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200818 | 1.00 | KMT2A (0.46) | KMT2AALDH1A1MAPK1ALOX15L3MBTL1 | |
| SCHEMBL3706423 | 0.98 | KMT2A (0.43) | KMT2AALDH1A1MAPK1ALOX15L3MBTL1 | |
| SCHEMBL997207 | 0.87 | CYP2D6 (0.43) | KMT2AALDH1A1MAPK1ALOX15L3MBTL1 | |
| SCHEMBL31631322 | 0.87 | — | — | |
| SCHEMBL996829 | 0.84 | ALDH1A1 (0.38) | KMT2AALDH1A1MAPK1ALOX15L3MBTL1 | |
| SCHEMBL13934134 | 0.79 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPK1ALOX15L3MBTL1 | |
| SCHEMBL20173448 | 0.79 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPK1ALOX15L3MBTL1 | |
| SCHEMBL11266483 | 0.79 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPK1ALOX15L3MBTL1 | |
| SCHEMBL27166971 | 0.79 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPK1ALOX15L3MBTL1 | |
| SCHEMBL6704692 | 0.77 | ALDH1A1 (0.46) | KMT2AALDH1A1MAPK1ALOX15RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204471-A1 | Compounds and Methods for Treating Autoimmune Disorders by Targeting HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204471-A1 | Compounds and Methods for Treating Autoimmune Disorders by Targeting HLA-DQ2 | HLA-DRB1, CD74, HLA-B | KMT2A 1995/4885ALDH1A1 3804/4885MAPK1 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.