Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31631322 | 1.00 | — | — | |
| SCHEMBL3706423 | 0.90 | KMT2A (0.43) | CYP2D6CYP2C19HIF1AALDH1A1ALOX15 | |
| SCHEMBL24564744 | 0.87 | KMT2A (0.46) | CYP2D6CYP2C19HIF1AALDH1A1ALOX15 | |
| SCHEMBL1200818 | 0.87 | KMT2A (0.46) | CYP2D6CYP2C19HIF1AALDH1A1ALOX15 | |
| SCHEMBL996829 | 0.80 | ALDH1A1 (0.38) | CYP2D6CYP2C19HIF1AALDH1A1ALOX15 | |
| SCHEMBL2418029 | 0.79 | HSD17B10 (0.42) | CYP2D6CYP2C19HIF1AALDH1A1ALOX15 | |
| SCHEMBL126839 | 0.78 | CYP2D6 (0.43) | CYP2D6CYP2C19HIF1AALDH1A1L3MBTL1 | |
| SCHEMBL12589530 | 0.77 | — | — | |
| SCHEMBL17274238 | 0.77 | — | — | |
| SCHEMBL7835313 | 0.75 | CYP2D6 (0.32) | CYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040947-B2 | Primer composition | MITSUI CHEMICALS, INC. (JP) | 2018-08-07 | — | — | US | disclosed |
| EP-2258780-B1 | PRIMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-20110014483-A1 | PRIMER COMPOSITION | MITSUI CHEMICALS, INC. | 2011-01-20 | — | — | US | disclosed |
| EP-2258780-A1 | PRIMER COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2010-12-08 | — | — | EP | disclosed |