Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483307 | 0.97 | MMP1 (0.51) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL7483298 | 0.97 | MMP1 (0.51) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL7481131 | 0.93 | MMP1 (0.58) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL7481144 | 0.93 | MMP1 (0.58) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL7487114 | 0.85 | EGFR (0.60) | GLSLMNAHDAC1HDAC3HDAC2 | |
| SCHEMBL7487107 | 0.85 | EGFR (0.60) | GLSLMNAHDAC1HDAC3HDAC2 | |
| SCHEMBL7488537 | 0.84 | FSCN1 (0.52) | MMP1MMP2MMP9GLSLMNA | |
| SCHEMBL7480810 | 0.84 | MMP1 (0.55) | MMP1MMP2MMP9GLSLMNA | |
| SCHEMBL7480813 | 0.84 | MMP1 (0.55) | MMP1MMP2MMP9GLSLMNA | |
| SCHEMBL7488527 | 0.84 | FSCN1 (0.52) | MMP1MMP2MMP9GLSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064273-A2 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 2001-01-03 | — | — | EP | claimed |
| WO-1999047507-A2 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-23 | — | — | WO | claimed |