Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 1/20 | 0.51 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483298 | 1.00 | MMP1 (0.51) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL7835345 | 0.97 | MMP1 (0.52) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL7481144 | 0.92 | MMP1 (0.58) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL7481131 | 0.92 | MMP1 (0.58) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL7487107 | 0.86 | EGFR (0.60) | GLSFSCN1HDAC1LMNAKMT2A | |
| SCHEMBL7487114 | 0.86 | EGFR (0.60) | GLSFSCN1HDAC1LMNAKMT2A | |
| SCHEMBL7485660 | 0.86 | RAB9A (0.56) | POLBGLSHDAC1LMNAKMT2A | |
| SCHEMBL7485669 | 0.86 | RAB9A (0.56) | POLBGLSHDAC1LMNAKMT2A | |
| SCHEMBL7480813 | 0.83 | MMP1 (0.55) | MMP1MMP2MMP9GLSFSCN1 | |
| SCHEMBL7480810 | 0.83 | MMP1 (0.55) | MMP1MMP2MMP9GLSFSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | claimed |
| US-6150385-A | VIRICIDE WITH ACTIVITY AGAINST CYTOMEGALO VIRUS (CMV), HERPES VIRUS INCLUDING VARICELLA ZOSTER VIRUS, THE EPSTEIN-BARR VIRUS, THE HERPES SIMPLEX VIRUS, AND THE HUMAN HERPES VIRUS TYPE 8 (HHV-8) | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-21 | — | — | US | claimed |
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | disclosed |