Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | BCR | P11274 | 2/20 | 0.43 |
| ▸ | CENPE | Q02224 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784578 | 0.95 | LMNA (0.53) | LMNAPOLBGAAMAPK14KMT2A | |
| SCHEMBL784099 | 0.88 | NPSR1 (0.49) | LMNAPOLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL783552 | 0.85 | LMNA (0.51) | LMNAPOLBGAAKMT2AGLA | |
| SCHEMBL3428080 | 0.82 | KMT2A (0.44) | POLBGAAKMT2AGLACYP1A2 | |
| SCHEMBL784021 | 0.82 | LMNA (0.45) | LMNAPOLBGAAKMT2AGLA | |
| SCHEMBL3421041 | 0.79 | LMNA (0.44) | LMNAPOLBGAAKMT2AGLA | |
| SCHEMBL5200663 | 0.78 | KMT2A (0.53) | LMNAPOLBGAAKMT2ATRPM8 | |
| SCHEMBL3428069 | 0.77 | LMNA (0.48) | LMNAPOLBGAAKMT2ATRPM8 | |
| SCHEMBL784102 | 0.75 | GLA (0.43) | LMNAPOLBGAAKMT2AGLA | |
| SCHEMBL784676 | 0.73 | ALDH1A1 (0.47) | LMNAGAAKMT2AGLACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694648-B1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER SAS (FR) | 2015-07-29 | — | — | EP | disclosed |
| EP-1720865-B1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2014-12-31 | — | — | EP | disclosed |
| EP-1651604-B1 | N-´2-(2-PYRIDINYL)ETHYL BENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2014-11-12 | — | — | EP | disclosed |
| EP-1694649-B1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2014-01-22 | — | — | EP | disclosed |
| US-8318777-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2012-11-27 | — | — | US | disclosed |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2012-03-22 | — | — | US | disclosed |
| US-8071627-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2011-12-06 | — | — | US | disclosed |
| US-7960391-B2 | Heterocyclylethylbenzamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-06-14 | — | — | US | disclosed |
| US-7932396-B2 | 2-pyridinylcycloalkylbenzamide derivatives and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| EP-1597252-B1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | BAYER SAS (FR) | 2011-02-09 | — | — | EP | disclosed |
| EP-1531673-B1 | NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE | BAYER CROPSCIENCE SA (FR) | 2006-01-04 | — | — | EP | disclosed |
| EP-1597252-A1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | Bayer CropScience S.A. (FR) | 2005-11-23 | — | — | EP | disclosed |
| WO-2005103004-A1 | 2-PYRIDINYLCYCLOALKYLBENZAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2005-11-03 | — | — | WO | disclosed |
| US-20050234110-A1 | Novel 2-pyridylethylbenzamide derivative | BAYER SAS (FR) | 2005-10-20 | — | — | US | disclosed |
| WO-2005058828-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE S.A. (FR) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058833-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2005-06-30 | — | — | WO | disclosed |
| EP-1531673-A2 | NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE | Bayer CropScience S.A. (FR) | 2005-05-25 | — | — | EP | disclosed |
| WO-2005014545-A2 | N-′2-(2-PYRIDINYL) ETHYLBENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE S.A. (FR) | 2005-02-17 | — | — | WO | disclosed |
| WO-2004074280-A1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | BAYER CROPSCIENCE SA (FR) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004016088-A2 | NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE | BAYER CROPSCIENCE S.A. (FR) | 2004-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234110-A1 | Novel 2-pyridylethylbenzamide derivative | PNPO, PAH, CNPY2 | LMNA 1920/4885POLB 1198/4885GAA 639/4885 |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP3A5 | LMNA 2942/4885POLB 4528/4885GAA 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.