Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247750 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7836982 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3245733 | 0.83 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL7837508 | 0.83 | PTGS2 (0.84) | PTGS2PTGS1 | |
| SCHEMBL3239863 | 0.76 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL3246464 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3240378 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3246624 | 0.74 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3242173 | 0.72 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL3252364 | 0.72 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802917-B1 | ARYL SUBSTITUTED 5,5 FUSED AROMATIC NITROGEN COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | MERCK FROSST CANADA INC (CA) | 2001-11-07 | — | — | EP | claimed |
| EP-0802917-A1 | ARYL SUBSTITUTED 5,5 FUSED AROMATIC NITROGEN COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | MERCK FROSST CANADA INC. (CA) | 1997-10-29 | — | — | EP | claimed |
| US-5552422-A | Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1996-09-03 | — | — | US | claimed |
| WO-1996021667-A1 | ARYL SUBSTITUTED 5,5 FUSED AROMATIC NITROGEN COMPOUNDS AS ANTI-INFLAMMATORY AGENTS | MERCK FROSST CANADA INC. (CA) | 1996-07-18 | — | — | WO | claimed |