Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 3/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6160387 | 0.99 | BRD4 (0.36) | BRD4AURKAAURKBNPY1RNPY2R | |
| SCHEMBL7835940 | 0.91 | MEN1 (0.35) | BRD4AURKAAURKBJAK2JAK3 | |
| SCHEMBL6159299 | 0.90 | KMT2A (0.40) | BRD4AURKAAURKBJAK2JAK3 | |
| Hydrochloric Acid SCHEMBL6159808 | 0.90 | MEN1 (0.34) | BRD4AURKAAURKBJAK2JAK3 | |
| Hydrochloric Acid SCHEMBL6159666 | 0.89 | KMT2A (0.39) | AURKAAURKBJAK2JAK3MEN1 | |
| SCHEMBL7858511 | 0.89 | AURKA (0.36) | AURKAAURKBJAK2JAK3APP | |
| SCHEMBL7835165 | 0.88 | AURKA (0.36) | AURKAAPPMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6158829 | 0.88 | AURKA (0.35) | AURKAAURKBJAK2JAK3APP | |
| SCHEMBL7824312 | 0.88 | AURKA (0.38) | AURKAAURKBMEN1KMT2ACTSS | |
| Hydrochloric Acid SCHEMBL6162784 | 0.87 | AURKA (0.35) | AURKAAPPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |